Preparative and Process HPLC Following are links to publications on this website featuring preparative and process applicatIons of Vydac HPLC columns, media, and related issues.

Application Notes:
HTML		#9601:	Strong Cation-Exchange and Reversed-Phase Purification of a Synthetic Peptide
HTML		#9603:	Cleaning of Reversed-Phase Columns Used for Synthetic Peptides
HTML		#9702:	A New Chemically-Resistant and Heat-Stable Reversed-Phase Column for Protein and Peptide Separations
HTML		#9801:	Oligonucleotide Purification and Analysis by Anion-Exchange and Reversed-Phase Chromatography
HTML		#9802:	Designing Purification Methods for Hydrophobic Peptides: Solubility Trials Can Be the Key
HTML		#9803:	Optimizing Peptide Purifications
HTML		#9807:	Process Scale-up of Protein and Polypeptide Separations
HTML		#9808:	Ion-Exchange Separations of Peptides
HTML		#9809:	The Concept of a Resolution Mixture in Developing and Validating Process Chromatographic Methods
HTML		#9901:	Reversed-Phase Purification of Protein from a Recombinant Fusion
HTML		#9903:	Cation-Exchange Chromatography of Peptides

Newsletter Articles:
	Spring 2000	Article #1: Reversed-Phase Preparative and Process Chromatography for Protein Purification Article #2: New Reversed-Phase Polymer Packings for Preparative Protein and Peptide LC
	Fall 1999	Article #4: Vydac Reversed-Phase Columns Aid in Purification of Recombinant Alzheimer's Proteins
	Summer 1999	Article #3: Cation-Exchange Chromatography of Peptides: Effects of pH and organic modifier
	Spring 1999	Article #3: Purification of Synthetic Oligonucleotides: Phosphodiesters, Phosphorothioates, Reversed Phase and Anion Exchange
	Fall 1998	Article #2: Purification of Synthetic Oligonucleotides
	Summer 1998	Article #1: Optimum Peptide Purification: Effects of Pore-Size, Buffers, pH, and Chemistry Article #4: Reversed-Phase Adsorbents Available in Bulk: 1 Kg to 100 Kg or more for Preparative and Process LC Article #6: Developing a Chromatographic Process for Purification of Insulin Article #7: The Concept of a Resolution Mixture: Its Role in Developing and Validating Process Chromatographic Methods
	Spring 1998	Article #2: Purification of a Lipid Peptide (continued): Developing a Method for Analysis Article #3: Scaling Up from Preparative to Process: Calculating the Desorbing Solvent or Salt Concentration for a Protein or Polypeptide
	Winter 1998	Article #2: Reversed-Phase Column Cleaning: SDS is OK! Article #4: Designing Separations for Difficult Peptides: Solubility trials can be the key
	Fall 1997	Article #2: Reversed-Phase Purification of Recombinant ß-Amyloid Peptide Article #3: Purification of a Synthetic 135-Base Oligonucleotide
	Summer 1997	Article #3: Effects of Column Length in Peptide Ion Exchange Article #4: Vydac's Unique Silica Article #7: Oligonucleotide Purification and Analysis by Ion Exchange
	Spring 1997	Article #3: 2-D Peptide Separations Article #4: Virtually Indestructible Reversed-Phase

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